How to use Prolia?

Prolia (denosumab) is a shot used to help with bone health. Here’s what you need to know: What is Prolia used for?

Osteoporosis: For postmenopausal women and men at high risk of fractures.

Glucocorticoid-induced osteoporosis: For both men and women at high risk of fractures.

Bone loss from androgen deprivation therapy (ADT): Helps men with nonmetastatic prostate cancer who are at high risk of fractures.

Bone loss from aromatase inhibitor therapy: Helps women with breast cancer who are at high risk of fractures.

How does it work?

Prolia stops cells that break down bone, making bones stronger.

Administration: Given as a shot every 6 months in the upper arm, upper thigh, or abdomen. Patients should also take calcium (1000 mg daily) and vitamin D (at least 400 IU daily).

Common side effects

For women (postmenopausal osteoporosis): Back pain, arm and leg pain, high cholesterol, muscle pain, bladder infection.

For men (osteoporosis): Back pain, joint pain, cold symptoms (runny nose or sore throat).

For glucocorticoid-induced osteoporosis: Back pain, bronchitis, headache, high blood pressure.

Mild side effects: Itchiness, sciatica (pain from lower back to leg), upper respiratory infections (like a cold).

Always talk to your doctor for personalized advice!

References 2020 Prolia Self injection Video E c08 website optimized (youtube.com). Prolia: Uses, Dosage, Side Effects, Warnings - Drugs.com. How Does Prolia® (denosumab) Work?.